Scientists Reveal How LSD reduces the Brain’s ‘Energy Landscape’

A crew of researchers has discovered proof that LSD (lysergic acid diethylamide) is the reason for the mental barriers that limit our thinking. 

Park Singleton, a doctoral candidate at Cornell University in New York who participated in the study, said that “Usually, our thoughts and the information we receive are filtered by our previous experience. However, if this filtering is eliminated And inhibition, you will see the world in a new light. You will gain a whole new perspective.” 

To reach this conclusion, Singleton and his colleagues analyzed functional magnetic resonance brain scans of placebo and LSD patients. They observed four different activity patterns of changes in the brain. Half of these patterns occur in the part of the brain dedicated to sensory activity (driving activity), and the other half occurs in the top-down processing part of the brain. Scientists have found that when LSD is used, the brain spends more time on activities driven by the senses and requires less energy to change states. 

In a new article that has not yet been peer-reviewed, the researchers explain in more detail how a specific receptor called 5-HT2a causes the drug to have this effect. According to Rebus’s model of psychedelic molecules tested during research, the brain acts as a predictive engine. Interpret new information based on previous experiences and beliefs. Under LSD, the situation has changed. 

According to The Guardian, David Nutt, professor of neuropsychopharmacology at Imperial University in London, was not involved in the study. He said that the effect of psychedelics can make you “go back to a state where bits of the brain that haven’t spoken since you were a baby can cross-talk,” allowing users to get new insight into old problems. 

This research may have a future impact on how psychedelics can help people with mental illness. “In frustration/depression, people are trapped in constant thoughts. It is like thinking of a tram,” Nut said. “The psychedelic drug interrupted the process, allowing people to escape.”